Association of Methadone Dose with Substance Use and Treatment Retention

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This study examined methadone dose and treatment retention among pregnant women with opioid use disorder. Treatment for non-pregnant individuals with methadone doses = 60 mg per day has been associated with improved treatment retention and decreased opioid misuse; while the treatment routes are the same for pregnant and non-pregnant individuals, no studies previously existed that could replicate the findings in pregnancy. Results from this study showed a significant positive relationship between average daily methadone dose during pregnancy and treatment retention. Women who received treatment of = 60 mg of methadone throughout their pregnancies were more likely to remain in treatment and provide urine samples that were negative for illicit drugs during their pregnancies, but not during the first 60 days postpartum.

Related Topics

  • Behavioral Health
  • Medications for Addiction Treatment (MAT)
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